内窥镜检查是空心器官内最广泛使用的癌症和息肉检测的医疗技术。但是，由于启蒙源方向，内窥镜获得的图像经常受到照明人工制品的影响。当内窥镜的光源姿势突然变化时，存在两个主要问题：产生过度曝光和不受欢迎的组织区域。这两种情况可能导致因影响区域缺乏信息而导致误诊，或者在非侵入性检查过程中使用了各种计算机视觉方法的性能（例如，大满贯，运动结构，光流，光流）。这项工作的目的是两倍：i）引入一种由生成对抗技术生成的新合成生成的数据集和ii），并探索在过度暴露和未渗透的照明中探索基于浅层和深度学习的基于浅的基于学习的图像增强方法条件。除了在7.6 fps左右的运行时间外，还通过基于深网的LMSPEC方法获得了最佳定量结果（即基于公制的结果）

Credit scoring models are the primary instrument used by financial institutions to manage credit risk. The scarcity of research on behavioral scoring is due to the difficult data access. Financial institutions have to maintain the privacy and security of borrowers' information refrain them from collaborating in research initiatives. In this work, we present a methodology that allows us to evaluate the performance of models trained with synthetic data when they are applied to real-world data. Our results show that synthetic data quality is increasingly poor when the number of attributes increases. However, creditworthiness assessment models trained with synthetic data show a reduction of 3\% of AUC and 6\% of KS when compared with models trained with real data. These results have a significant impact since they encourage credit risk investigation from synthetic data, making it possible to maintain borrowers' privacy and to address problems that until now have been hampered by the availability of information.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Despite the impact of psychiatric disorders on clinical health, early-stage diagnosis remains a challenge. Machine learning studies have shown that classifiers tend to be overly narrow in the diagnosis prediction task. The overlap between conditions leads to high heterogeneity among participants that is not adequately captured by classification models. To address this issue, normative approaches have surged as an alternative method. By using a generative model to learn the distribution of healthy brain data patterns, we can identify the presence of pathologies as deviations or outliers from the distribution learned by the model. In particular, deep generative models showed great results as normative models to identify neurological lesions in the brain. However, unlike most neurological lesions, psychiatric disorders present subtle changes widespread in several brain regions, making these alterations challenging to identify. In this work, we evaluate the performance of transformer-based normative models to detect subtle brain changes expressed in adolescents and young adults. We trained our model on 3D MRI scans of neurotypical individuals (N=1,765). Then, we obtained the likelihood of neurotypical controls and psychiatric patients with early-stage schizophrenia from an independent dataset (N=93) from the Human Connectome Project. Using the predicted likelihood of the scans as a proxy for a normative score, we obtained an AUROC of 0.82 when assessing the difference between controls and individuals with early-stage schizophrenia. Our approach surpassed recent normative methods based on brain age and Gaussian Process, showing the promising use of deep generative models to help in individualised analyses.

Weakly-supervised object detection (WSOD) models attempt to leverage image-level annotations in lieu of accurate but costly-to-obtain object localization labels. This oftentimes leads to substandard object detection and localization at inference time. To tackle this issue, we propose D2DF2WOD, a Dual-Domain Fully-to-Weakly Supervised Object Detection framework that leverages synthetic data, annotated with precise object localization, to supplement a natural image target domain, where only image-level labels are available. In its warm-up domain adaptation stage, the model learns a fully-supervised object detector (FSOD) to improve the precision of the object proposals in the target domain, and at the same time learns target-domain-specific and detection-aware proposal features. In its main WSOD stage, a WSOD model is specifically tuned to the target domain. The feature extractor and the object proposal generator of the WSOD model are built upon the fine-tuned FSOD model. We test D2DF2WOD on five dual-domain image benchmarks. The results show that our method results in consistently improved object detection and localization compared with state-of-the-art methods.

The renewed interest from the scientific community in machine learning (ML) is opening many new areas of research. Here we focus on how novel trends in ML are providing opportunities to improve the field of computational fluid dynamics (CFD). In particular, we discuss synergies between ML and CFD that have already shown benefits, and we also assess areas that are under development and may produce important benefits in the coming years. We believe that it is also important to emphasize a balanced perspective of cautious optimism for these emerging approaches

This paper presents a proof-of-concept method for classifying chemical compounds directly from NMR data without doing structure elucidation. This can help to reduce time in finding good structure candidates, as in most cases matching must be done by a human engineer, or at the very least a process for matching must be meaningfully interpreted by one. Therefore, for a long time automation in the area of NMR has been actively sought. The method identified as suitable for the classification is a convolutional neural network (CNN). Other methods, including clustering and image registration, have not been found suitable for the task in a comparative analysis. The result shows that deep learning can offer solutions to automation problems in cheminformatics.

Planning is an extraordinary ability in which the brain imagines and then enacts evaluated possible futures. Using traditional planning models, computer scientists have attempted to replicate this capacity with some level of success but ultimately face a reoccurring limitation: as the plan grows in steps, the number of different possible futures makes it intractable to determine the right sequence of actions to reach a goal state. Based on prior theoretical work on how the ecology of an animal governs the value of spatial planning, we developed a more efficient biologically-inspired planning algorithm, TLPPO. This algorithm allows us to achieve mouselevel predator evasion performance with orders of magnitude less computation than a widespread algorithm for planning in the situations of partial observability that typify predator-prey interactions. We compared the performance of a real-time agent using TLPPO against the performance of live mice, all tasked with evading a robot predator. We anticipate these results will be helpful to planning algorithm users and developers, as well as to areas of neuroscience where robot-animal interaction can provide a useful approach to studying the basis of complex behaviors.

在推荐系统中，项目可能会接触到各种用户，我们想了解新用户对现有项目的熟悉。这可以作为异常检测（AD）问题进行配置，该问题区分“普通用户”（名义）和“新用户”（异常）。考虑到物品的庞大数量和用户项目配对数据的稀疏性，在每个项目上独立应用传统的单任务检测方法很快就变得困难，而项目之间的相关性则被忽略。为了解决这个多任务异常检测问题，我们建议协作异常检测（CAD）共同学习所有任务，并通过任务之间的嵌入编码相关性来学习所有任务。我们通过条件密度估计和条件可能性比估计来探索CAD。我们发现：$ i $）估计似然比的学习效率更高，并且比密度估计更好。 $ ii $）提前选择少量任务以学习任务嵌入模型，然后使用它来启动所有任务嵌入是有益的。因此，这些嵌入可以捕获任务之间的相关性并推广到新的相关任务。

检测会计异常是财务报表审核中的反复挑战。最近，已经提出了源自深度学习（DL）的新方法来审核声明的基本会计记录的大量。但是，由于它们的大量参数，这种模型表现出固有不透明的缺点。同时，隐藏模型的内部运作通常会阻碍其现实世界的应用。该观察结果在财务审计中尤其如此，因为审计师必须合理地解释和证明其审计决定是合理的。如今，已经提出了各种可解释的AI（XAI）技术来应对这一挑战，例如Shapley添加说明（Shap）。但是，在经常在财务审核中应用的无监督DL中，这些方法在编码变量级别上解释了模型输出。结果，人类审计师通常很难理解自动编码器神经网络（AENNS）的解释。为了减轻此缺点，我们提出（重塑），该属性在汇总属性级别上解释了模型输出。此外，我们引入了一个评估框架，以比较XAI方法在审计中的多功能性。我们的实验结果表明，经验证据表明，与最先进的基线相比，重塑结果是多功能解释的。我们将这种属性级别的解释视为在财务审计中采用无监督的DL技术的必要下一步。